Multivariate statistical analysis of tissue basophils in acute radiation sickness
Datsenko, A.V.; Shikhodyrov, V.V.; Korneliuk, V.A.
Arkhiv Anatomii Gistologii i Embriologii 90(1): 69-72
1986
ISSN/ISBN: 0004-1947 PMID: 3954605 Document Number: 271249
By means of mark scale estimation method, discriminant and factor analyses, changes in integral indices on the state of mast cells in the rat mesentery have been investigated in dynamics of medullary, intestinal and cerebral forms of an acute radiation sickness. The integral indices are calculated basing on the morphometric parameters of the cells, that are obtained after the histological preparations are treated in a special automatic system for analysing images. At the medullary form of the acute radiation sickness, the greatest structural rearrangements of the mast cells take place during the first hours after the radiation, as well as during the climax of the disease, at the intestinal form, the analogous changes are revealed 1-3 days after the effect, and at the cerebral form--3 h after the radiation. The integral indices, calculated by means of the three methods, are well correlated with each other.