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M monoclonal macroglobulinemia induced in BALB/C mice. Effect on blood cholesterol and its significance

Clerc, G.; Dumon, M.F.; Seiwert, E.; Fleurentin, J.; Clerc, M.

Annales de Biologie Clinique 44(4): 384-388

1986

ISSN/ISBN: 0003-3898
PMID: 3098142
Document Number: 270554
BALB/C mice have been inoculated with a monoclonal IgM secreting hybridoma and have developed an hypocholesterolemia strongly dependent of the hypermacroglobulinemia M obtained (P less than 0.001). Cholesterolegram shows cholesterol is carried on the monoclonal IgM fraction. This result has been established in comparison with a lot of mice treated with the same no secreting hybridoma and a lot of untreated-mice, in these cases cholesterolemia is not modified. The whole aminoacids sequence of this IgM being nearly achieved, it is thinked of check the hypocholesterolemic activity of several parts of this immunoglobulin.

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Bucciarelli, E. 1971: Isogenic transplants, in adults and neonatal hosts, of pulmonary tumors induced with hydrazine sulfate in BALB-c-Cb-Se mice: ultrastructural study Lavori Dell'istituto di Anatomia e Istologia Patologica Universita Degli Studi di Perugia 31(1): 10-34
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