Significance of monoclonal macroglobulinemia
Leporrier, M.
La Revue du Praticien 43(3): 298-301
1993
ISSN/ISBN: 0035-2640 PMID: 8502959 Document Number: 410128
A monoclonal IgM protein in the plasma results from an expansion of a B lymphoid clone which encompasses a spectrum of different diseases: transient clones, monoclonal gammopathy of undetermined significance, Waldenström's macroglobulinemia and other B lymphoid malignancies, or primary amyloidosis. The main symptoms are related to the M component concentration and specific properties, the tumor development or both. Prognosis best correlates with the underlying histologic disorder.
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