Scintigraphic diagnosis of primary hepatocellular carcinoma in the woodchuck (Marmota monax)
Kallfelz, F.A.; Hornbuckle, W.E.; Harvey, H.J.; Wallace, R.J.; Potkewitz, L.G.; Roth, L.; Tennant, B.C.
American Journal of Veterinary Research 47(3): 573-576
1986
ISSN/ISBN: 0002-9645 PMID: 3008602 Document Number: 270416
Hepatic imaging with 99mTc-sulfur colloid was used to diagnose primary hepatocellular carcinoma (PHC) in woodchucks infected with woodchuck hepatitis virus (WHV). Based on imaging results, 6 of 12 WHV-infected woodchucks had space-occupying hepatic lesions, and all 6 had PHC. Of the remaining woodchucks, 2 did not have PHC, 2 had discrete tumors (less than 1 cm diameter), 1 had miliary small tumors, and 1 had tumors located near the great vessels. Hepatic imaging was a valuable technique for diagnosis of PHC in WHV-infected woodchucks.