Gastroduodenal electric activity, in situ, during anesthesia and recovery. Study in chronic electrode-carrying rats
de Lavernhe-Lemaire, M.C.; Decaud-Laroche, J.; Boiron, M.; Thouvenot, J.
Archives Internationales de Physiologie et de Biochimie 94(1): 19-28
1986
ISSN/ISBN: 0003-9799 PMID: 2425766 Document Number: 270244
The effect of anaesthesia (sodium pentobarbital, two various doses) was studied in the rat with chronic gastric and duodenal electrodes. Gastric and duodenal electrical activity was recorded in pre- and peranesthesia period. All rhythmic slow and fast components are slowed in the same condition of time when an important decrease of central temperature is observed (external controlled temperature 22 degrees C). Gastric slow wave (650 microV, frequency normal level 5.6 c/min) decreases about 40% in 180 min. The waking arise after 5h30, 1h30 before the complete recuperation of the previous rhythm. For half dose conditions, gastric slow wave frequency decreases about 30% in 30 min; waking up occurs in 90 min. Gastric emptying complex observed previously. Is only observed during 20-30 min of the initial period of the anaesthesia at 50 mg/kg, and throughout the anaesthesia at 25 mg/kg.