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Effect of cross-linking agents on electron transport and proton transfer in the mitochondrial respiratory chain

Konev, S.V.; Rudenok, A.N.; Chernook, N.N.; Lyskova, T.I.; Aksentsev, S.L.

Biofizika 30(4): 704-706

1985

ISSN/ISBN: 0006-3029
PMID: 2996622
Document Number: 266899
The effect of protein cross-linkage on proton translocation and electron transport in mitochondria respiratory chain was studied. Dimethylsuberimidate (1 mM) or dicyclohexyl carbodiimide (50 g/ml) inhibit proton translocation with concomitant stimulation of respiration. It is concluded that the definite level of dynamic mobility of proteins is needed for proton translocation.

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