Lymphocyte uroporphyrinogen synthase in the diagnosis of lymphoma and its follow-up
Lahav, M.; Epstein, O.; Schoenfeld, N.; Shaklai, M.; Atsmon, A.
Harefuah 108(5): 243-245
1985
ISSN/ISBN: 0017-7768 PMID: 4007683 Document Number: 265549
Uroporphyrinogen synthase activity is increased in the peripheral lymphocytes in various lymphoproliferative diseases. Determination of the activity of this enzyme is a useful diagnostic test for these diseases. Four patients are described in whom this determination influenced the diagnostic work-up and therapeutic management. Its importance in the diagnosis of lymphoma, in establishing complete remission and in the early detection of relapses was demonstrated in these patients.