Vitamin a and cancer incidence in a retirement community
Paganini-Hill, A.; Ross, R.K.; Gray, G.E.; Henderson, B.E.
National Cancer Institute Monograph 69: 133-135
1985
ISSN/ISBN: 0083-1921 PMID: 3834322 Document Number: 263969
The use of vitamin A supplements and the risk of cancer was examined in a cohort of 11,888 residents of a retirement community near Los Angeles, California. After 2 1/2 years of follow-up, 445 incident cancers occurred in 435 of the study participants. Overall, the relative risk of cancer for supplement users versus nonusers was 1.0. In a subset of 32 randomly selected individuals, the 14 supplement users had a significantly higher mean serum retinol level (86 micrograms/dl) than did the 18 nonusers (74 micrograms/dl).