Influence of genetic polymorphisms on responsiveness to dietary fat and cholesterol
Ye, S.Q.; Kwiterovich, P.O.
American Journal of Clinical Nutrition 72(5 Suppl): 1275s-1284s
2000
ISSN/ISBN: 0002-9165 PMID: 11063469 DOI: 10.1093/ajcn/72.5.1275sDocument Number: 261983
Evidence for the influence of structural and non-structural DNA polymorphisms in genes relevant to lipid metabolism on the responsiveness to dietary fat and cholesterol is reviewed. The following genes are discussed: apolipoprotein genes (APOA1, APOA4, APOC3, APOB, APOE); lipid processing enzyme genes (lipoprotein lipase, cholesteryl ester transfer protein, lecithin-cholesterol acyltransferase);and lipoprotein receptor genes.