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Biological significance of ascorbic acid (vitamin C) in human health - a review

Khalid Iqbal; Alam Khan; Khattak, M.M.A.K.

Pakistan Journal of Nutrition 3(1): 5-13

2004

DOI: 10.1186/1475-2891-3-5
Document Number: 260552
The recognition of vitamin C (ascorbic acid) is associated with history of an unrelenting search for the cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential for the development and maintenance of connective tissues. It plays an important role in bone formation, wound healing and the maintenance of healthy gums. Vitamin C plays an important role in a number of metabolic functions including the activation of folic acid, the conversion of cholesterol to bile acids, and the conversion of tryptophan to serotonin. Vitamin C is an antioxidant that protects body from the damage of free radicals. It is used as a therapeutic agent in many diseases and disorders. Vitamin C protects the immune system, reduces the severity of allergic reactions and helps fight infections.

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