Effect of protein calorie malnutrition and calcium deficiency on hepatic iso-metallothioneins in Cd-exposed monkeys
Paliwal, V.K.; Kambadur, R.; Prasad, R.; Nath, R.
Biochemistry International 11(3): 397-405
1985
ISSN/ISBN: 0158-5231 PMID: 3933513 Document Number: 259389
Oral administration of cadmium results in the induction of metallothionein in liver of rhesus monkeys subjected to protein calorie malnutrition and calcium deficiency. Metallothionein was resolved into three iso-proteins viz. MTa, MTb & MTc which varied in their quantities and metal composition in these nutritional stress conditions. 'MTc' was the major iso-protein in protein calorie malnourished monkeys, while 'MTb' predominated in the calcium deficient group.