Kinetics of cellular adhesion to different materials used in implants
Cannas, M.; Carando, S.; Denicolai, F.; Poncino, A.
Bollettino della Societa Italiana di Biologia Sperimentale 61(3): 461-465
1985
ISSN/ISBN: 0037-8771 PMID: 4027036 Document Number: 256924
The authors expose their observations about the kinetics of cell adesion on two materials used as implants in orthopaedic surgery, AISI, 316 L steel and passivated titanium. The kinetics of cell attachment have been compared: an initial rapid increase of bound radioactivity was observed on passivated titanium (in 5 - 30 min) and after this rapid reaction the number of attached cells increased only slowly, during the following 30 min. After incubation of 90 min, almost all cells became attached. Kinetic of BHK cell attachment on AISI 316 L differs significantly: almost all added cells were attached in 90 min but the rapid increase of attachment is observed only during the first 30 min. These observations are important for the comprension of adhesion mechanisms and characterize the properties of biocompatibility of implant materials.