Electrophysiological study in patients with chronic hepatic insufficiency
Pierelli, F.; Pozzessere, G.; Sanarelli, L.; Valle, E.; Rizzo, P.A.; Morocutti, C.
Acta Neurologica Belgica 85(5): 284-291
1985
ISSN/ISBN: 0300-9009 PMID: 4072614 Document Number: 256316
Twenty patients affected by chronic hepatic insufficiency were studied by means of combined EEG, VEP and BAEP recordings. Subjects were classified, according to Parsons-Smith criteria, in grade 0 (without any clinical sign) and grade I (with minimal mental disturbances). In group 0 patients an elevated incidence of VEP alterations (40%) was observed, while EEG and BAEP recordings were less frequently (10%) abnormal. In group I patients a high degree of EEG (60%), VEP (70%) and BAEP (70%) abnormalities was found. Mean latency and interpeak interval values in group I patients were significantly prolonged if compared with the grade 0 and control groups. No correlations were found between electrophysiological data and blood biochemical parameters examiend (ammoniemia, aminoacidemic pattern).