The Papillon-Lefevre syndrome (keratosis palmoplantaris with periodontopathy) . Treatment with etretinate
Wehrmann, W.; Traupe, H.; Happle, R.
Der Hautarzt; Zeitschrift für Dermatologie Venerologie und verwandte Gebiete 36(3): 173-175
1985
ISSN/ISBN: 0017-8470 PMID: 3158626 Document Number: 254988
The Papillon-Lefèvre syndrome is an autosomal recessive gene defect characterized by transgredient palmoplantar hyperkeratosis and periodontopathia leading to loss of the teeth. The syndrome is described in a 28-year-old man who had lost all of his teeth at the age of 10 years. Treatment with etretinate resulted in a marked improvement of the palmar and plantar skin lesions.