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Effect of adrenergic receptor blockers on the cardio-respiratory response to cow's urine concoction in rats

Oyebola, D.D.; Ariwodola, J.O.

African Journal of Medicine and Medical Sciences 14(1-2): 11-19

1985

ISSN/ISBN: 0309-3913
PMID: 2863966
Document Number: 254319
The influence of .alpha. and .beta. adrenoceptor blockers on the cardio-respiratory effects of cow's urine concoction (CUC) in rats was studied. Phenoxybenzamine abolished the pressor response observed in the untreated animal while propranolol had no effect on blood pressure response. The .alpha.-blocked animals also developed significant post-injection hypotension. Electrocardiographic abnormalities seen in the control group were ameliorated by .beta.-blockers but .alpha.-blockers had no such effect. CUC caused an initial depression of respiration with short apnoeic phases and an increase in pulmonary ventilation. The latter was significantly decreased by .alpha. and .beta. adrenoceptor blockers. Adrenoceptors play an important role in the cardio-respiratory effects of CUC.

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Saksena, S.K.; Gokhale, S.V. 1972: Effect of some adrenergic receptor blocking drugs on early pregnancy in rats Indian Journal of Medical Research 60(2): 281-283
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Dotzer, F.; Gromer, H. 1993: Indications spectrum for beta-1-selective adrenergic receptor blockers Fortschritte der Medizin 111(24): 382-384
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Tsutsumi, H.; Ohsaki, M.; Seki, K.; Chiba, S. 1999: Respiratory syncytial virus infection of human respiratory epithelial cells enhances both muscarinic and beta2-adrenergic receptor gene expression Acta Virologica 43(4): 267-270
Shao, Y.; McCarthy, K.D. 1993: Quantitative relationship between alpha 1-adrenergic receptor density and the receptor-mediated calcium response in individual astroglial cells Molecular Pharmacology 44(2): 247-254
Renouard, A.; Widdowson, P.S.; Millan, M.J. 1994: Multiple alpha 2 adrenergic receptor subtypes. I. Comparison of [3H]RX821002-labeled rat R alpha-2A adrenergic receptors in cerebral cortex to human H alpha2A adrenergic receptor and other populations of alpha-2 adrenergic subtypes Journal of Pharmacology and Experimental Therapeutics 270(3): 946-957
Aoyama, N. 2007: Effect of combination therapy with angiotensin Ii type i receptor and aldosterone receptor blockers in heart failure Nihon Rinsho. Japanese Journal of Clinical Medicine 65(Suppl 5): 145-149
Maitrya, B.B.; Lippold, O.C. 1970: Cardio-respiratory effects of passing polarizing current to the cerebral cortex of rats Indian Journal of Physiology and Pharmacology 14(4): 239-244
Chourashy, B.K. 1988: Anti-anginal drugs: calcium channel blockers, beta-adrenergic blockers and nitrates Journal of the Indian Medical Association 86(10): 274-276