Current issues in the development of a vaccine against HIV infection
Davey, R.T.
Ear Nose and Throat Journal 69(7): 497-505
1990
ISSN/ISBN: 0145-5613 PMID: 2205474 Document Number: 254274
There are a variety of complex issues involved in current efforts to design and test a safe and effective vaccine against HIV-1 infection. Although a number of important insights already have been gained, future advances in vaccine development must overcome a number of obstacles. These include the lack of a suitable animal model for HIV-1 infection and our incomplete understanding of the protective immune response in this disease as well as uncertainties about the most appropriate strategy for large-scale testing of promising candidate vaccines.
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