Development of an immunocontraceptive vaccine. Current status
Feng, H.; Sandlow, J.I.; Sparks, A.E.; Sandra, A.
Journal of Reproductive Medicine 44(9): 759-765
1999
ISSN/ISBN: 0024-7758 PMID: 10509297 Document Number: 499681
Development of an effective and modern contraceptive vaccine is a key factor in the global issue of regional population growth as well as agricultural, medical, economic and social development. A review was done of the current medical literature concerning development of an immunocontraceptive vaccine and relative molecular biology technology. Various approaches have been taken to identify candidate-specific antigens for immunocontraceptive development, such as sperm, zona pellucida and hormonal antigens. Suppressed fertility and the reversibility of these effects on mammalian species, including humans, have been demonstrated. The successful results obtained so far support the continued investigation for an effective immunocontraceptive vaccine.