Endometrial hyperplasia detected by ambulatory endometrial biopsy
Szamborski, J.; Teter, J.; Wasilewska, B.
Patologia Polska 36(1): 47-57
1985
ISSN/ISBN: 0031-3114 PMID: 4047744 Document Number: 254146
In 71 (16.3%) women out of 436 with the endometrial hyperplasia determined by ambulatory endometrial biopsy, bleeding was the indication for such procedure, while in 192 (44%) women biopsy was taken after identifying clinical signs accepted as risk factors for endometrial neoplasia development. Detected hyperplasia in about 20% of cases had the features of adenomatous hyperplasia; at the same time in bleeding patients with this type of hyperplasia there dominated development of the whole examined endometrium (dispersed), whereas in the group of women with risk factors but asymptomatic focal growth occurred. Focal adenomatous hyperplasia was rarely (in 6.8% cases) accompanied by bleeding; this type of growth was most frequently observed in women with hyperplasia of endometrium in past history (32.6%) and then in patients with Stein-Lewenthal's syndrome and fibrocystic disease of breast (20.4 and 16.2% respectively). Dispersed adenomatous hyperplasia of the whole examined endometrium was most frequently found in bleeding patients (17% of patients in the "metrorrhage" subgroup). Out of the total number of 55 patients with adenomatous hyperplasia (dispersed and focal inclusively), 9% of patients developed endometrial carcinoma. Out of 15 patients with dispersed hyperplasia, 5 developed endometrial carcinoma. Their follow-up period was 18 years.