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Difference in the inhibitory effect of linoleic acid hydroperoxide on prostacyclin biosynthesis between cultured endothelial cells from human umbilical cord vein and cultured smooth muscle cells from rabbit aorta

Sasaguri, Y.; Morimatsu, M.; Nakashima, T.; Tokunaga, O.; Yagi, K.

Biochemistry International 11(4): 517-521

1985

ISSN/ISBN: 0158-5231
PMID: 3910047
Document Number: 252840
The biosynthesis of prostacyclin in cultured endothelial cells from human umbilical cord vein was inhibited by linoleic acid hydroperoxide at a concentration of 0.1 nmol/ml (in terms of malondialdehyde), while that in cultured smooth muscle cells from rabbit aorta was inhibited only at a higher concentration of the hydroperoxide (5.0 nmol/ml).

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