Maintenance of preload reserve of right cardiac function by administration of TNG during rapid administration of plasma expander (Haemaccel) under halothane anesthesia
Muteki, T.; Aragaki, T.; Goto, S.; Shimizu, D.; Sueyoshi, F.; Kono, I.; Tokutomi, Y.; Takagi, T.
Masui. Japanese Journal of Anesthesiology 34(7): 945-952
1985
ISSN/ISBN: 0021-4892 PMID: 3932707 Document Number: 252831
In order to evaluate if volume load due to a rapid infusion of plasma expander Haemaccel could be satisfactorily relieved by i.v. administration of TNG , mean circulatory filling pressure (Pms), arterial to venous capacitance ratio (CV/CA), right ventricular work index (RVWI), pulmonary vascular resistance (PVR), cardiac output (venous return), electromechanical index of right atrial pressure waves (RaEMI:cardiodynamic index of atrial kick), and the pressure difference between Y and X valley pressure values of right atrium, (.DELTA.RaPx-y; cardiodynamic index of right atrium as conduit) were measured with use of fiber-optic measuring system during surgery. Administration of TNG would prevent volume overloading due to rapid administration of Haemaccel with maintenance of preload reserve in right sided heart. Fall of Pms with an increase of CV/CA under TNG administration was restored by rapid infusion of Haemaccel. .DELTA.RaPx-y was maintained during rapid administration of Haemaccel under i.v. administration of TNG. RVWI and PVR which were increased by rapid infusion of Haemaccel were suppressed by TNG maintaining the right ventricular preload reserve.