Metabolism of halothane after its repeated administration in man
Atallah, M.M.; Geddes, I.C.
Middle East Journal of Anaesthesiology 5(2): 85-91
1978
ISSN/ISBN: 0544-0440 PMID: 581777 Document Number: 136574
Metabolism of halothane following its repeated administration, was studied in three patients by estimating the blood bromide concentrations before, during and after halothane anaesthesia. In one patient, the blood halothane concentration was measured during and after its administration. The fraction of halothane metabolised was found to be increased after its repeated administration. This was proved by the rapid clearance of halothane and the increased blood bromide concentration.