Lymphocyte subpopulations and cell mediated cytotoxicity in acute non-lymphoid leukemia (ANLL) patients in complete remission (CR) and off-therapy

De Rossi, G.; Fontana, L.; de Sanctis, G.; Petti, M.C.; Pasqualetti, D.; Guglielmi, C.; Vitale, A.; Mandelli, F.

Biomedicine and PharmacoTherapy 39(5): 245-247

1985


ISSN/ISBN: 0753-3322
PMID: 4084659
Document Number: 252517
An assessment of the lymphocyte sub-populations and cell mediated cytotoxicity was made in 12 adults with acute non-lymphoid leukemia after stopping chemotherapy. No significant differences were found between ANLL and controls, for absolute lymphocyte count, %SIg/+ cells, Fc gamma + cells and ERFC. The OKT4+/OKT8+ was reduced in ANLL. Leu-7+ cells were significantly higher in ANLL. Moreover it appears that in ANLL lymphocyte function is restored early after stopping chemotherapy.

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