Hypovolemic shock caused by increased capillary permeability associated with monoclonal gammopathy. New case and review of the literature

Piette, A.M.; De Rohan-Chabot, P.; Chapman, A.; Gepner, P.; Brenot, F.; Loirat, P.

Annales de Medecine Interne 136(7): 572-574

1985


ISSN/ISBN: 0003-410X
PMID: 4091359
Document Number: 250868
The authors report another case of hypovolaemic shock due to increased capillary permeability and review previous reports in the medical literature. It is a rare condition with all patients presenting hypovolaemic shock of sudden onset with varying degrees of hypoproteinaemia and increased haematocrit. A monoclonal globulin peak is usually observed on serum electrophoresis during and between episodes of shock. The pathological role of this globulin in the increased capillary permeability has not been established.

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