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Natural variability of respiratory-syncytial viruses, their interference and reproduction characteristics

Yurlova, T.J.; Zoshchenkova NYa; Karpova, L.S.

Acta Virologica 29(4): 279-284

1985

ISSN/ISBN: 0001-723X
PMID: 2864830
Document Number: 247119
Over a 5-year observation period in a children-institution community, the severity of respiratory-syncytial (RS) virus infection varied within a broad range depending on biological properties of the circulating virus population. The type of virus population was characterized by a complex of biological features, namely, the extent of their reproduction and interference in tissue cultures of different origin at optimal incubation temperature. The dynamics of genetic alterations in respect to these properties within 1976-1980 was established. Moreover, the seasonal variability of the strains with respect to these properties has been determined.

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