Protective effects of O- (beta-hydroxyethyl) -rutosides (HR) against adriamycin-induced toxicity in rats
Gulati, O.P.; Nordmann, H.; Aellig, A.; Maignan, M.F.; Mcginness, J.
Archives Internationales de Pharmacodynamie et de Therapie 273(2): 323-334
1985
ISSN/ISBN: 0003-9780 PMID: 4004421 Document Number: 245679
Adriamycin daily for 28 days (5 days before and 23 days after the 1st injection of adriamycin), improved adriamycin-induced clinical signs and symptoms (loss of body wt, hypothermia and decreased general vitality). It tended to increase cardiac output and stroke volume.
Document emailed within 1 workday
Related Documents
Gábor, M. 1981: The effect of O-(beta-hydroxyethyl)-rutosides (HR) on the skin capillary resistance of rats Arzneimittel-Forschung 31(3): 442-445Chertow, B.S.; Webb, M.D.; Leidy, J.W.; Cordle, M.B. 1989: Protective effects of retinyl palmitate on streptozotocin- and alloxan-induced beta cell toxicity and diabetes in the rat Research Communications in Chemical Pathology and Pharmacology 63(1): 27-44
Cappelli, R.; Pecchi, S.; Oberhauser, V.; Forconi, S.; Di Perri, T. 1987: Efficacy of O-(beta-hydroxyethyl)-rutosides at high dosage in counteracting the unwanted activity of oral contraceptives on venous function International Journal of Clinical Pharmacology Research 7(4): 291-299
Bernardini, C.; Del Tacca, M.; Danesi, R.; Della Torre, P. 1986: The influence of amrinone on cardiac toxicity induced by adriamycin in rats Archives Internationales de Pharmacodynamie et de Therapie 283(2): 243-253
Mirkovitch, V.; Borgeaud, J.; Meyer, S.; Niebs, P. 1972: Prevention of experimental thrombosis with 0-( -hydroxyethyl)-rutosides Helvetica Chirurgica Acta 39(1): 379-382
Zhao, M-Qi.; Wu, W-Kang.; Zhao, D-Yang.; Liu, Y.; Liu, Y.; Liang, T-Wen.; Luo, H-Chuan. 2005: Protective effects of Sini decoction on adriamycin-induced heart failure and its mechanism: role of superoxide dismutase Zhongguo Zhong Yao Za Zhi 30(14): 1111-1114
Xu, Z.; Wu, W.; Lan, T.; Zhang, X. 2009: Protective effects of extract of Ginkgo biloba on adriamycin-induced heart failure and its mechanism: role of ghrelin peptide Zhongguo Zhong Yao Za Zhi 34(21): 2786-2789
Imamura, T. 1984: Protective effect of drug metabolism inducer and inhibitor on O,O,S-trimethyl phosphorothioate induced delayed toxicity in rats Proceedings of the Western Pharmacology Society 27: 155-161
Verbin, R.S.; Diluiso, G.; Farber, E. 1973: Protective effects of cycloheximide against 1-beta-D-arabinosylcytosine-induced intestinal lesions Cancer Research 33(9): 2086-2093
Yin, J.; Zhai, S.; Guo, W.; Hu, Y.; Shi, L. 2002: Protective and rescue effects of transgenic bFGF/GFP expression mediated by cationic liposome on gentamicin-induced guinea pig cochlear toxicity Zhonghua Yi Xue Za Zhi 82(17): 1192-1194
Sharma, A.K.; Kumar, S.; Chashoo, G.; Saxena, A.K.; Pandey, A.K. 2014: Cell cycle inhibitory activity of Piper longum against A549 cell line and its protective effect against metal-induced toxicity in rats Indian Journal of Biochemistry and Biophysics 51(5): 358-364
Deng, X.L.; Qiu, P.L.; Liu, J.T.; Chen, S.Y. 1993: Protective effects of 3, 6-dimethamidodibenzopyriodinium citrate on myocardial injury induced by ischemia and reperfusion in rats Zhongguo Yao Li Xue Bao 14(4): 367-369
Wang, J.L.; Zhu, W.Y.; Wang, Z.J. 1988: Protective effects of prostaglandin E2 on pancreatic islet B cells of rats with alloxan induced diabetes Chinese Medical Journal 101(3): 165-170
Goraca, A.; Józefowicz-Okonkwo, G. 2007: Protective effects of early treatment with lipoic acid in LPS-induced lung injury in rats Journal of Physiology and Pharmacology: An Official Journal of the Polish Physiological Society 58(3): 541-549
Zhang, J.; Peng, R.-y.; Ren, J.-h.; Li, J.; Wang, S.-m.; Gao, Y.-b.; Dong, Q.; Zhao, L.; Liu, S.-c. 2011: The protective effects of Aduola Fuzhenglin on the heart injury induced by microwave exposure in rats Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 29(5): 367-370
Wang, L.-j.; Luo, W.-f.; Wang, H.-h.; Ni, G.-h.; Ye, Y.; Li, D.; Liu, C.-f. 2010: Protective effects of uric acid on nigrostriatal system injury induced by 6-hydroxydopamine in rats Zhonghua Yi Xue Za Zhi 90(19): 1362-1365
Caviale, P.; McClellan, E.L. 1981: Adriamycin toxicity. Effects in subsequent anesthesia and surgery Journal of the Kansas Medical Society 82(12): 553; 574
Strauss, M.; Porras, N. 2007: Differential expression of HSP70 and ultrastructure of heart and liver tissues of rats treated with adriamycin: protective role of L-carnitine Investigacion Clinica 48(1): 33-43
Anurag, P.; Rajamohan, T. 2003: Beneficial effects of tender coconut water against isoproterenol induced toxicity on heart mitochondrial activities in rats Indian Journal of Biochemistry and Biophysics 40(4): 278-280
Zhang, H.; Piao, H.; Li, M.; Wu, Z.; Piao, S.; Jin, Z. 1995: Protective effects of methanolic extract of Oenanthe stolonifera (Roxb.) Wall. ex DC. on myocardial injury induced by ischemia and reperfusion in rats Zhongguo Zhong Yao Za Zhi 20(1): 44-46; 63