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Incorporation of radioactive phosphorus into creatine phosphate of the rabbit myocardium in experimental coronary insufficiency

Voronkov, G.S.; Kul'chitskiĭ, O.K.; Sabko, V.E.; Bogatskaia, L.N.

Ukrainskii Biokhimicheskii Zhurnal 57(4): 67-69

1985

ISSN/ISBN: 0201-8470
PMID: 4035797
Document Number: 245583
It is shown that under conditions of experimental limitation of coronary blood flow in rabbits the intensity of radioactive label (32P) incorporation into creatine phosphate lowers essentially. This evidences for inhibition of creatine phosphorylation in mitochondria under ischemia due to a decrease in the activity of a mitochondrial isoenzyme of creatine kinase.

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