Contractility of ischemic and intact regions of the myocardium during experimental occlusion of the coronary vessels
Gruzdev, A.K.; Kiandzhuntseva, E.A.; Popov, V.G.
Kardiologiia 22(11): 57-63
1982
ISSN/ISBN: 0022-9040 PMID: 7154509 Document Number: 194464
In acute experiments on 32 dogs the authors studied the time course of the contractile function of the myocardium after coronary occlusion in the area of ischaemia and in segments of the left ventricle far removed from the ischaemic zone. Local contractility was studied with the aid of M-echographic method through changes in the thickness of the ventricular wall during the contraction. As a result of experimental investigation the authors distinguish 3 types of myocardial asynergy: hypokinesia, hypokinesia with elements of dyskinesia in the initial part of the ejection period and dyskinesia. A quantitative assessment of the degree of asynergy is offered on the strength of the amplitude of movement of the ischemized wall, percentage of its maximum systolic thickening and the local phase structure of the myocardial contraction. The most sensitive index of the state of general contractility of the left ventricle after limited ischaemia of the myocardium proved to be the end diastolic pressure and the ratio between the stroke work of the left ventricle and the end diastolic pressure.