Components of the creatine kinase system in the myocardium with experimental disturbance of coronary blood flow
Voronkov, G.S.
Ukrainskii Biokhimicheskii Zhurnal 54(2): 167-170
1982
ISSN/ISBN: 0201-8470 PMID: 7080219 Document Number: 195552
Certain key parameters of energy metabolism in a complex mechanism of energy transport in the myocardium cells were studied in experiments on dogs with dosed limitation of the coronary blood flow (by 90%) as well as in experiments on rabbits with the intravenous injection of vasopressin (0.2 units per 1 kg of mass). Animals of all groups under study revealed essential changes in the content of creatine phosphate and in the activity of creatine phosphokinase as compared with the control groups. A possible role of creatine phosphokinase is discussed in the processes of myocardium function energy supply under conditions of creatine phosphate deficiency during a slightly pronounced ischemia.