Effects of low-dose OCs on weight in women with Central European nutritional habits and lifestyle
Lech, M.M.; Ostrowska, L.
Contraception 66(3): 159-162
2002
ISSN/ISBN: 0010-7824 PMID: 12384203 DOI: 10.1016/s0010-7824(02)00352-9Document Number: 243731
The aim of the study was to evaluate the acceptance and tolerance of combined low-dose oral contraceptives (OCs) (containing 20 micro g ethinylestradiol and 75 micro g gestodene) in a cohort of Polish women, and to present a relationship between the use of combined OCs and changes in body weight. Changes in body weight with combined low-dose OC have not been demonstrated in placebo-controlled trials, nor were such trials performed in a population whose nutritional/dietary habits and lifestyle resemble that of the population of Poland. We performed the clinical study on a group of 800 patients living in several regions of Poland. Patients used the low-dose OC for a period of 6 months. They were assessed every third cycle of OC use (initial examination and examinations after three and six cycles of OC use). On the basis of this investigation, a relationship between OC use and weight gain was not found.