Risk of vertebral fracture after menopause: identification of subjects at high risk by dual photon absoprtionometry

Coutris, G.; Talbot, J.N.; Kiffel, T.; Paus, L.; Milhaud, G.

Biomedicine and PharmacoTherapy 39(1): 35-39

1985


ISSN/ISBN: 0753-3322
PMID: 4027349
Document Number: 242820
Dual photon absorptionometry of bone is used to detect in an exposed population those subjects who are high risk of fracture and also to follow up the evolution of these patients. 37 women who have suffered fractures have been compared to 41 women without fractures of similar age distribution. A highly significant correlation between body height and Bone Mineral Content (BMC) of the lumbar spine is found in the control group thus allowing the calculation of the expected BMC value for each patient. A crushing index is defined as the ratio of the observed BMC value to the expected one. Using this index, instead of the two more usual modes of BMC expression, leads to an improvement of the predictive estimation of fracture risk. The predictive value of such indices should still be improved. With this aim, further determinations of indices are desirable. The following requirements should be borne in mind: The physical data should be easily obtainable e.g. body height and weight and the meaning of the index based on these easily verifiable factors they should be easily understood.

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