Glomerular changes in interstitial kidney diseases
Pfaltz, M.; Briner, J.
Schweizerische Medizinische Wochenschrift 114(6): 204-209
1984
ISSN/ISBN: 0036-7672 PMID: 6701502 Document Number: 241327
49 kidney specimens of patients with primary interstitial kidney disease (hydronephrosis in 12, tubulo-interstitial nephritis in 13, analgesic nephropathy in 10, adult polycystic renal disease in 9, oxalosis in 4, and renal dysplasia in 1) were examined for glomerular lesions. Light microscopic investigation showed severe focally and segmentally accentuated glomerular changes in 13 cases (27%). Lesions resembling focal sclerosis were found in 11 cases and focal-segmental mesangial proliferation in 2 cases. The results reveal that glomerular lesions occur frequently in primary interstitial kidney disease and can be found in all of the above-mentioned diagnostic entities.