Quantitative gas chromatographic determination of pantolactone
Moĭseenok, A.G.; Slyshenkov, V.S.; Sunozova, E.V.; Gurinovich, V.A.
Voprosy Meditsinskoi Khimii 30(1): 126-128
1984
ISSN/ISBN: 0042-8809 PMID: 6710930 Document Number: 241268
A gas chromatographic procedure is described for quantitative estimation of alpha-hydroxy-beta 1 beta-dimethyl-gamma-butyrolactone (pantolactone). The chromatography was carried out using "LHM-8MD" apparatus equipped with a flame ionization detector. Columns with chromaton N-AW modified by 5% silicone XE-60 were used, helium served as a gas-carrier, chloroform - as a solvent, gamma-butyrolactone was introduced as a standard. High resolving power was achieved in experiments with the column for the analyzed substances and the standard at the sensitivity of the method 7.6 X X 10(-4) mmole/ml.