The hyperglycemic effect of N-methylglucamine antimonate (glucantime)
Ceyhan, M.; Kinik, E.; Diker, S.; Yurdakök, M.; Dilmen, U.
Mikrobiyoloji Bulteni 18(4): 185-189
1984
ISSN/ISBN: 0374-9096 PMID: 6513823 Document Number: 239439
We applied meglumine antimonate (Glucantime) to 10 albino mice in a dose of 15-30 mg/kg for first three days and then 60 mg/kg for twelve days intramuscularly, and double dose to another 10 mice. No drug was administered to 9 mice which were control group. On 16th day, there were hyperglycemia, parenchymal degeneration and inflammation in liver which were more marked in double dose group. The monitoring of blood glucose of the patients with kala-azar receiving Glucantime, was suggested.