Fibronectin and other immunologic parameters in chronic polyarthritis
Siegmeth, W.; Minar, E.; Graninger, W.; Pirich, K.; Zazgornik, J.
Zeitschrift für Rheumatologie 43(1): 27-29
1984
ISSN/ISBN: 0340-1855 PMID: 6201023 Document Number: 238171
In 20 patients with rheumatoid arthritis the plasma fibronectin concentrations were measured and correlated with the levels of C-reactive protein, alpha 1-antitrypsin, alpha 2-macroglobulin, fibrinogen, C3, C4 complement fractions and alpha 2-antiplasmin in serum respectively plasma. Patients with rheumatoid arthritis showed plasma fibronectin concentrations within reference levels. However, the concentrations of C-reactive protein, alpha 1-antitrypsin, alpha 2-antiplasmin, fibrinogen and C3-complement fraction were significantly higher in comparison to the healthy controls. The results indicate that fibronectin does not belong to the group of "acute phase proteins". Measurement of plasma fibronectin give no additional information about the activity of rheumatoid arthritis.