Limbic structures of the brain and the pathogenesis of neuroses
Simonov, P.V.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 84(11): 1665-1670
1984
ISSN/ISBN: 0044-4588 PMID: 6543081 Document Number: 236891
The understanding of the nature of neurosis as secondary to a chronic conflict of motivations intolerable for a given type of neurons system has prompted the choice of experimental neurosis in rats in the form of switching heterogeneous conditional reflexes according to E. A Asratyan. Bilateral hippocampectomy eliminated the neurotic symptoms whereas following the bilateral destruction of the amygdala the coflict of motivations can be evaded only by facilitating the formation of the evidently predominant need. The consequences of neurotigenic impacts depend on the individual peculiarities of rats, which may be elicited by simulating Eysenck's parameters. Neurosis arises as a result of an impaired interaction betwee the frontal neocortex, hippocampus, amygdala and hypothalamus. An important role is played by cerebral hypoxia resulting from chronic emotional stress.