Antibiotic distribution in normal and osteomyelitic bone
Fitzgerald, R.H.
Orthopedic Clinics of North America 15(3): 537-546
1984
ISSN/ISBN: 0030-5898 PMID: 6472833 Document Number: 235489
Antibiotics are able to penetrate normal and osteomyelitic bone in a fashion that permits concentrations equivalent to those found in the serum following intravenous administration. There is no osseous barrier or gradient in osseous tissue to antibiotic penetration.
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