CD4+ and CD8+ T-lymphocyte subsets in Zambian children

Ndhlovu, Z.; Ryon, J.J.; Griffin, D.E.; Monze, M.; Kasolo, F.; Moss, W.J.; Ndhlovu, Z; Ryon, J.J; Griffin, D.E; Monze, M; Kasolo, F; Moss, W.J

doi:10.1093/tropej/50.2.94

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CD4+ and CD8+ T-lymphocyte subsets in Zambian children

Ndhlovu, Z.; Ryon, J.J.; Griffin, D.E.; Monze, M.; Kasolo, F.; Moss, W.J.

Journal of Tropical Pediatrics 50(2): 94-97

2004

ISSN/ISBN: 0142-6338

PMID: 15088798

DOI: 10.1093/tropej/50.2.94

Document Number: 233423

Age-related changes in lymphocyte subsets in HIV-uninfected Zambian children are described. The total lymphocyte count and numbers of CD4+ and CD8+ T-lymphocytes declined with increasing age, while the percentage of CD4+ and CD8+ T-lymphocytes changed little during childhood. Girls between the ages of 12 and 71 months had a higher percentage of CD4+ T-lymphocytes and a higher CD4:CD8 ratio than did boys of a similar age.