Comparison between midazolam and thiopentone-based balanced anaesthesia for day-case surgery
Crawford, M.E.; Carl, P.; Andersen, R.S.; Mikkelsen, B.O.
British Journal of Anaesthesia 56(2): 165-169
1984
ISSN/ISBN: 0007-0912 PMID: 6691877 Document Number: 229960
In a randomized study of 100 women (ASA 1-2 -fentanyl-N2O. The induction time (the time recorded until disappearance of the palpebral reflex) was significantly longer in the M group (40 s) than in the T group (31 s). There were no significant differences in heart rate or arterial pressure between the 2 groups. Thirty minutes after the termination of surgery the degree of awareness, estimated by means of Glasgow Coma Scale, was lower in the M group. After 60 and 180 min the scores were equal. During recovery more patients experienced side-effects in the T group than in the M group, the difference being statistically significant 72 h afterdischarge when 66 and 34% of the patients complained of side-effects, respectively. M is apparently as suitable as T for the induction of anesthesia in day-case surgery.