The normal testis: structure, function and recent endocrinologic advances
Demoulin, A.; Lambotte, R.; Franchimont, P.
Journal de Gynecologie Obstetrique et Biologie de la Reproduction 13(1): 3-12
1984
ISSN/ISBN: 0368-2315 PMID: 6725875 Document Number: 226151
The embryology, the anatomy and the histology of the testis are briefly described. Then, the endocrinology of the organ is explained. Under the influence of pituitary LH, Leydig cells synthetize and release steroids that are principally testosterone. These act on the hypothalamo-pituitary axis, on the peripheral target organs and directly on the testis so as to control spermatogenesis and Sertoli cell function. Sertoli cells are implicated in spermatogenesis, steroidogenesis, and the synthesis of protein hormones and cybernin . Current knowledge about the antimullerian hormone, androgen binding protein, GnRH-like peptide, inhibin, testicular chalone, FSH receptor binding inhibitor and stimulator, PRL inhibiting substance and relaxin is reviewed.