Acute platelet activation induced by smoking. in vivo and ex vivo studies in humans
Schmidt, K.G.; Rasmussen, J.W.
Thrombosis and Haemostasis 51(2): 279-282
1984
ISSN/ISBN: 0340-6245 PMID: 6234677 Document Number: 225234
Indices of acute in vivo platelet activation in response to cigarette smoking were sought in 10 healthy subjects. Judging by platelet aggregate ratio, platelet factor 4 and beta-thromboglobulin measurements, platelet activation took place from 10 to 30 min after smoking in most subjects. These signs correlated well with the results of scintigraphic studies showing signs of accumulation of 111-In-labelled platelets in the spleen in response to smoking.
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