Adjuvant chemotherapy after surgery in advanced gastric cancer
Hirose, S.; Mano, K.; Kataoka, K.; Kitamura, M.; Tsutsui, N.; Ohara, T.; Kimura, H.; Hamaya, K.
Gan no Rinsho. Japan Journal of Cancer Clinics 30(14): 1767-1772
1984
ISSN/ISBN: 0021-4949 PMID: 6439912 Document Number: 224142
Two hundred and fifty-four patients with advanced gastric cancer underwent radical surgery and ftorafur (FT) or 5-fluorouracil (5-FU) was orally administered as the adjuvant chemotherapy (ACT). Recurrence after ACT were analyzed by the quantification method II. As a result, it was found that: 1) ACT over 2 years could lower the recurrence rate, and careful follow-up is still necessary up to 4 years, and 2) after the remission induction therapy with mitomycin C and/or 5-FU and cytarabine, 12 mg/kg/day of FT for the first year and 8 mg for the second year are advisable.