Vaginal contents show in vitro mutagenic activity

Wei, R.D.; Liu, G.X.; Yuan, C.C.; Ng, H.T.

Proceedings of the National Science Council Republic of China. Part B Life Sciences 8(1): 46-49

1984


ISSN/ISBN: 0255-6596
PMID: 6531416
Document Number: 221864
In Millipore filtrate of some vaginal douching, mutagens were readily detected by means of the Ames Salmonella test. Among 521 subjects, the samples of 76 cases (14.6%) were mutagenic in Salmonella typhimurium TA98 or/and TA100 in the presence or absence of S9 mixture. Dichloromethane and chloroform were found to extract the mutagens satisfactorily.

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