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Antitumor effect of new lymphokine OH-1 on BDF1 mice bearing Lewis lung carcinoma

Orita, K.; Miwa, H.; Yamashita, H.; Kurimoto, M.

Gan to Kagaku Ryoho. Cancer and ChemoTherapy 11(6): 1253-1256

1984

ISSN/ISBN: 0385-0684
PMID: 6428323
Document Number: 221492
Antitumor effect of new lymphokine extracted from BALL-1 cells derived from human acute lymphocytic leukemia was investigated using BDF1 mice bearing Lewis lung carcinoma. This antitumor lymphokine is called OH-1. The antitumor effect of OK-1 on transplanted main tumor was great, but less effective than cyclophosphamide. However, the antitumor effect on OH-1 on metastatic tumor was comparably high as with cyclophosphamide, both macroscopically and functionally.

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