Phenotypic characterization of skin-infiltrating cells in pagetoid reticulosis by monoclonal antibodies
Gonzalez, M.; Martin-Pascual, M.; San Miguel, J.; Caballero, M.D.; López Borrasca, A.
Acta Dermato-Venereologica 64(5): 421-424
1984
ISSN/ISBN: 0001-5555 PMID: 6208722 Document Number: 221182
The immunological characterization of the infiltrating cells in a patient with a disseminated form of Pagetoid reticulosis (PR) was carried out-in histological section and cell suspensions--by means of a panel of monoclonal antibodies and classical markers (E-rosette and surface immunoglobulins (SIg]. Most of the infiltrating cells were seen to be mature T-lymphocytes with a suppressor/cytotoxic phenotype (T11+, T3+, T8+, T4-). The results suggest that this variant of PR represents a special histological type of cutaneous T cell lymphoma.