Treatment of pagetoid reticulosis with intensity modulated radiation therapy

Mount, C.; Ferraro, D.; Gru, A.; Bradbury, M.; Cornelius, L.; Gay, H.

Dermatology Online Journal 20(10)

2014


ISSN/ISBN: 1087-2108
PMID: 25525999
Document Number: 676199
Pagetoid reticulosis, also known as Woringer-Kolopp disease, is a rare variant of cutaneous T-cell lymphoma usually presenting as an isolated patch or plaque on the extremities. Immunohistochemical staining of T-cell markers can be variable, but as the name implies the epidermotropic lymphocytes consistently display a "pagetoid" appearance. The following case demonstrates clearance of this condition with intensity modulated radiation therapy, whereas most cases are managed with electron beam therapy if radiation therapy is implemented.

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