Lactic acidosis and hypoglycemia: experimental evidence to show lactate prevents insulin induced seizures in rats
Guruprakash, G.H.; Rao, M.G.; Krishnan, E.C.; Poulose, K.P.
American Journal of the Medical Sciences 285(3): 34-37
1983
ISSN/ISBN: 0002-9629 PMID: 6342389 Document Number: 219759
A 52-year-old man with lactic acidosis and severe hypoglycemia was fully conscious and alert with a blood sugar of 8 mgs%. We believe normal level of consciousness was maintained due to the presence of hyperlactatemia. We show experimental evidence to suggest that lactate prevents the development of insulin-induced seizures in rats.