Fatal case of metformin-induced lactic acidosis after urography in a diabetic patient
Jamet, P.; Lebas de Lacour, J.C.; Christoforov, B.; Stern, M.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 56(9-10): 473-474
1980
ISSN/ISBN: 0037-1777 PMID: 6244670 Document Number: 159488
The authors report a new case of lactic-acidosis in a diabetic patient receiving metformin. This patient, after urography developed an acute renal failure and a fatal lactic acidosis. Risks of urography in diabetic patients and guidelines for use of metformin are recalled; careful assessment of risk versus benefit for every proposed urography in diabetic patients never use metformin if creatinin is over 140 micromoles/liter, if an urography must be undergone, metformin must be stopped 3 days before urography and resumed only 3 days after it, if renal function allows it.