Hepatitis and jaundice associated with measles in young adults. An analysis of 65 cases
Gavish, D.; Kleinman, Y.; Morag, A.; Chajek-Shaul, T.
Archives of Internal Medicine 143(4): 674-677
1983
ISSN/ISBN: 0003-9926 PMID: 6838292 Document Number: 219694
We analyzed the clinical course of 65 adult patients hospitalized because of measles during the years 1975 and 1981-1982. Liver involvement was found in 80% (52/65) of the patients, five patients had clinical jaundice. The disturbances of liver function tests reached their peak values between days 5 and 10 of the disease. In this study of measles in adulthood we have three observations of unusual interest: (1) hepatitis occurs commonly in the more severely ill patients and it may manifest clinically as jaundice; (2) long-term follow-up (up to seven years) shows a clear tendency to complete resolution of the liver damage; (3) there is a clear correlation between the severity of hepatic involvement and the occurrence of secondary bacterial infections.