Confirmation of putative HIV-1 group P in Cameroon

Vallari, A.; Holzmayer, V.; Harris, B.; Yamaguchi, J.; Ngansop, C.; Makamche, F.; Mbanya, D.; Kaptué, L.; Ndembi, N.; Gürtler, L.; Devare, S.; Brennan, C.A.; Vallari, A; Holzmayer, V; Harris, B; Yamaguchi, J; Ngansop, C; Makamche, F; Mbanya, D; Kaptué, L; Ndembi, N; Gürtler, L; Devare, S; Brennan, C.A

doi:10.1128/jvi.02005-10

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Confirmation of putative HIV-1 group P in Cameroon

Vallari, A.; Holzmayer, V.; Harris, B.; Yamaguchi, J.; Ngansop, C.; Makamche, F.; Mbanya, D.; Kaptué, L.; Ndembi, N.; Gürtler, L.; Devare, S.; Brennan, C.A.

Journal of Virology 85(3): 1403-1407

2011

ISSN/ISBN: 1098-5514

PMID: 21084486

DOI: 10.1128/jvi.02005-10

Document Number: 216175

We report the second human immunodeficiency virus (HIV) belonging to the new HIV type 1 (HIV-1) group P lineage that is closely related to the simian immunodeficiency virus found in gorillas. This virus was identified in an HIV-seropositive male hospital patient in Cameroon, confirming that the group P virus is circulating in humans. Results from screening 1,736 HIV-seropositive specimens collected in Cameroon indicate that HIV-1 group P infections are rare, accounting for only 0.06% of HIV infections. Despite its rarity, group P shows evidence of adaptation to humans.