Age-related changes in PHA and allogeneic reactivity of human T lymphocytes
Matej, H.; Myc, A.
Archivum Immunologiae et Therapiae Experimentalis 31(1): 33-38
1983
ISSN/ISBN: 0004-069X PMID: 6604509 Document Number: 214971
In fifty-four healthy individuals aged from 22 to 53 the response of lymphocytes to PHA stimulation and to stimulation with allogeneic lymphocytes were determined. A linear age-related decrease in reactivity to PHA (r = 0.500, P less than 0.01), as well as to allogeneic stimulation (r = 0.351, P less than 0.01) was found. The correlation between these two parameters of T lymphocyte function was weak (r = 0.207, not significant).
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